Angioedema Management

Discover effective strategies for Angioedema Management in this comprehensive article. Learn vital techniques such as treating airway obstruction through intubation and utilizing Epinephrine 1:1000 injections. Explore specific medication options, including Berinert, Ecallantide, and Icatibant, with recommended dosages.

• Treat Airway obstruction: Intubation
• Epinephrine 1: 1000 0.5 ml IM in anteriolateral thigh if anaphylaxis present. May repeat every 5 minutes.
• If on beta blockers give glucagon 1mg IV
• Fresh Frozen Plasma 10 ml/kg IV
• Specific Medication options:

1. Berinert 20 u/kg IV
2. Ecallantide 10 mg SQ upto 3 doses
3. Icatibant 30 mg SQ

• If identifiable allergen:

1. Diphenhydramine (Benadryl) 1mg/kg IV or IM (max 50 mg)
2. Ranitidine 1mg/kg IV
3. Solumedrol 250mg IV once followed by 125 mg IV q6h